A Summary of the Key Differences Between the FDA’s Drug and Dietary Supplement GMPs Share page: In general, the Part 111 GMP requirements, although similar, are less stringent and tend to be more flexible than the Part 211 GMP requirements. Document(s) to download: Summary-of-Key-Differences-Between-FDA-Drug-Dietary-Supplement-GMPs-03042015.pdf (147.02 KB) Issues: OTC Medicines Dietary Supplements Other Issues Quality Related Posts Press Releases and Statements CHPA Responds to HHS/FDA Announcement to Phase Out Petroleum-based Synthetic Dyes from America’s Food Supply Apr 22, 2025 Press Releases and Statements Health In Hand Foundation Announces Call for Nominations: 2025 U.S. Self-Care Marketing Awards Apr 22, 2025 Press Releases and Statements CHPA Applauds White House Executive Order Prioritizing Lower Drug Costs and Access to Self-Care Apr 17, 2025